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The episode opens with a flashback of Desmond Hume (Henry Ian Cusick), in the Phillipines, searching for a doctor to help his wife Penny Widmore (Sonya Walger), who is giving birth to their son, Charlie. In 2007, Desmond and Penny arrive in London, where Desmond plans to look for the mother of Daniel Faraday (Jeremy Davies), who is believed to be at Oxford University. However, the school has no record of either Faraday, even though Daniel was a professor there. Desmond searches Faraday's lab and meets a janitor who tells him that Faraday conducted experiments on a woman and provides an address for her. At her house, Desmond finds that the woman is in a vegetative state after experiencing temporal disassociation, similar to Desmond's experiences on the freighter (as seen in "The Constant"). He learns that Penny's father, Charles Widmore (Alan Dale), is not only paying her medical expenses, but also funded Daniel's research. Desmond confronts Widmore, who gives him the address of Daniel's mother in Los Angeles. Desmond returns to Penny, who agrees that they must travel to Los Angeles.